Christians in Gaza said that they had "lost a man who fought every day in every direction to protect this small herd of his."
As early as October 2023, the late Pope had highlighted the well-being of the hostages in his remarks on October 7, 2023, and on the ensuing Israel-Hamas war.
The following rituals mark the end of one papacy and the start of the next.
"The global Catholic community bids farewell to a leader who recognised the burning issues of our day and called attention to them," Dutch Prime Minister Dick Schoof said.
Pope Francis suggested the global community study whether Israel's military campaign in Gaza constitutes a genocide of the Palestinian people.
Francis, originally from Argentina, was the first Catholic pontiff from the Americas and began his career as a Jesuit priest in Argentina.
"I appeal to the warring parties: Call a ceasefire, release the hostages and come to the aid of a starving people that aspires to a future of peace," the Pope's Easter message said.
The 88-year-old pontiff, who is limiting his public appearances on doctors' orders, skipped an outdoor ceremony for Good Friday, the day Christians mark Jesus' crucifixion.
The 88-year-old pontiff is gradually making more public appearances as he recovers from the biggest health crisis in his 12 years in the role.
King Charles and Queen Camilla had been due to make a formal state visit to the Vatican, but postponed their plans after doctors prescribed Francis two months of rest.